Description

(2R,3S)-Methyl 2-(2-Bromophenyl)-3-(Trifluoromethyl)-1,4-Oxathiane-3-Carboxylate is a high-value, stereochemically defined chiral building block featuring a unique oxathiane heterocycle. This compound is engineered to provide a rigid, functionalized scaffold critical for the synthesis of complex molecules, particularly in advanced pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients with specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, especially in areas targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Research: Used in the synthesis of novel, stereoselective pesticides and herbicides where the specific spatial arrangement of the bromophenyl and trifluoromethyl groups is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry in chemical reactions.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Item	Details
Product Name	(2R,3S)-Methyl 2-(2-Bromophenyl)-3-(Trifluoromethyl)-1,4-Oxathiane-3-Carboxylate
CAS No.	876156-56-8
Molecular Formula	C14H12BrF3O3S
Molecular Weight	397.21 g/mol
Synonyms	Methyl (2R,3S)-2-(2-bromophenyl)-3-(trifluoromethyl)-1,4-oxathiane-3-carboxylate; (2R,3S)-Methyl 2-(o-bromophenyl)-3-(trifluoromethyl)-1,4-oxathiane-3-carboxylate; (2R,3S)-2-(2-Bromophenyl)-3-(trifluoromethyl)-1,4-oxathiane-3-carboxylic acid methyl ester; CAS 876156-56-8; Chiral oxathiane carboxylate ester; 1,4-Oxathiane-3-carboxylic acid, 2-(2-bromophenyl)-3-(trifluoromethyl)-, methyl ester, (2R,3S)-
EINECS	Contact for details

Quality Control

Every batch of (2R,3S)-Methyl 2-(2-Bromophenyl)-3-(Trifluoromethyl)-1,4-Oxathiane-3-Carboxylate is produced and tested under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.