Description

(2R,3S)-Methyl 2-Phenyl-3-(Trifluoromethyl)-1,4-Oxathiane-3-Carboxylate is a high-value, chiral heterocyclic building block featuring a unique oxathiane ring system. This compound matters for its role as a sophisticated intermediate in the synthesis of complex molecules, where its defined stereochemistry and trifluoromethyl group are critical for modulating biological activity and physicochemical properties. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances compound stability and efficacy.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new stereoselective synthetic methodologies.
• Material Science Precursor: Potential building block for specialty polymers or liquid crystals that benefit from its rigid, fluorinated structure.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(2R,3S)-Methyl 2-Phenyl-3-(Trifluoromethyl)-1,4-Oxathiane-3-Carboxylate
CAS No.	876156-53-5
Molecular Formula	C14H15F3O3S
Molecular Weight	320.33 g/mol
Synonyms	Methyl (2R,3S)-2-phenyl-3-(trifluoromethyl)-1,4-oxathiane-3-carboxylate; (2R,3S)-2-Phenyl-3-(trifluoromethyl)-1,4-oxathiane-3-carboxylic acid methyl ester; 1,4-Oxathiane-3-carboxylic acid, 2-phenyl-3-(trifluoromethyl)-, methyl ester, (2R,3S)-; 876156-53-5; (2R,3S)-Methyl 2-phenyl-3-(trifluoromethyl)-1,4-oxathiane-3-carboxylate
EINECS	Contact for details

Quality Control

Our (2R,3S)-Methyl 2-Phenyl-3-(Trifluoromethyl)-1,4-Oxathiane-3-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.