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5-(Ethoxycarbonyl)-3-Pyridinyl Boronic Acid CAS NO 875781-62-7
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CAS No.:875781-62-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-(Ethoxycarbonyl)-3-Pyridinyl Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.
Application
- Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and other small molecule therapeutic development.
- Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific pyridine-based structures.
- Material Science: Serves as a monomer or precursor for creating functional polymers, organic electronic materials, and metal-organic frameworks (MOFs).
- Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis in medicinal chemistry.
- Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and coordination chemistry.
- Diagnostic Reagent Production: Intermediate in the synthesis of probes and labeling agents for biochemical assays and imaging.
Basic Information
| Product Name | 5-(Ethoxycarbonyl)-3-Pyridinyl Boronic Acid |
| CAS No. | 875781-62-7 |
| Molecular Formula | C8H10BNO4 |
| Molecular Weight | 194.98 g/mol |
| Synonyms | 5-(Ethoxycarbonyl)pyridine-3-boronic acid; 3-Pyridineboronic acid, 5-(ethoxycarbonyl)-; Ethyl 5-borono-3-pyridinecarboxylate; 5-Carbethoxy-3-pyridylboronic acid; (5-(Ethoxycarbonyl)pyridin-3-yl)boronic acid; 3-Borono-5-ethoxycarbonylpyridine; Ethyl 3-pyridinylboronate-5-carboxylate; CAS 875781-62-7 |
| EINECS | Contact for details |
Quality Control
Our 5-(Ethoxycarbonyl)-3-Pyridinyl Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Heavy Metals | ≤ 20 ppm |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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