Description

4-Chloro-6-(Phenylethynyl)Pyrimidin-5-Amine is a high-value pyrimidine derivative building block used in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, particularly in constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its pyrimidine core.
• Material Science: Serves as a precursor for organic electronic materials and specialty polymers due to its conjugated ethynylphenyl system.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes studying heterocyclic chemistry and cross-coupling reactions.

Basic Information

Product Name	4-Chloro-6-(Phenylethynyl)Pyrimidin-5-Amine
CAS No.	875340-49-1
Molecular Formula	C12H8ClN3
Molecular Weight	229.66 g/mol
Synonyms	5-Amino-4-chloro-6-(phenylethynyl)pyrimidine; 4-Chloro-6-(phenylethynyl)-5-pyrimidinamine; 4-Chloro-6-(phenylethynyl)pyrimidin-5-ylamine; 4-Chloro-6-(phenylethynyl)-5-aminopyrimidine; 6-(Phenylethynyl)-4-chloropyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Phenylethynyl)Pyrimidin-5-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.