Description

6-Chloro-5-Methylpicolinonitrile is a versatile and high-value heterocyclic building block, specifically a substituted picolinonitrile derivative. Its molecular structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients. Its precise reactivity profile enables the creation of targeted compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the discovery and production of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for developing specialty chemicals, ligands for catalysis, and functionalized polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Chloro-5-Methylpicolinonitrile
CAS No.	875293-89-3
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	6-Chloro-5-methylpyridine-2-carbonitrile; 5-Methyl-6-chloropicolinonitrile; 2-Cyano-6-chloro-5-methylpyridine; 6-Chloro-5-methyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 6-chloro-5-methyl-
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Methylpicolinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.