Description

R-Lenalidomide CAS NO 874946-00-6 is a specific enantiomer of the potent immunomodulatory and anti-angiogenic agent lenalidomide. This high-purity chiral intermediate is critical for pharmaceutical research and development, particularly in the synthesis of targeted therapeutics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors requiring precise stereochemistry for advanced drug discovery and process development programs.

Application

• Key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs) with specific stereochemical requirements.
• Critical building block for research and development of novel immunomodulatory and anticancer agents.
• Used in process chemistry for the scale-up and optimization of lenalidomide-related compound manufacturing.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Starting material for the preparation of deuterated or other isotopically labeled analogs for metabolic studies.
• Essential reagent in academic and industrial research exploring structure-activity relationships (SAR) of IMiDs®.

Basic Information

Product Name	R-Lenalidomide
CAS No.	874946-00-6
Molecular Formula	C13H13N3O3
Molecular Weight	259.26 g/mol
Synonyms	(R)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione; (R)-Lenalidomide; (R)-Revlimid; (2R)-2-(4-Amino-1-oxoisoindolin-2-yl)-5-oxopiperidine-1-carboxamide; (R)-CC-5013; UNII-8W6P7UGF2K; (R)-enantiomer of Lenalidomide
EINECS	Contact for details

Quality Control

Our R-Lenalidomide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.