Description

(5-Fluoro-2-Methoxy-Pyridin-3-Yl)-Methanol is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is designed for the efficient construction of complex pharmacophores and agrochemicals. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of novel organic electronic materials and liquid crystals due to its electron-withdrawing and structural properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(5-Fluoro-2-Methoxy-Pyridin-3-Yl)-Methanol
CAS No.	874822-98-7
Molecular Formula	C7H8FNO2
Molecular Weight	157.14 g/mol
Synonyms	3-(Hydroxymethyl)-5-fluoro-2-methoxypyridine; 5-Fluoro-2-methoxy-3-pyridinemethanol; (5-Fluoro-2-methoxypyridin-3-yl)methanol; 5-Fluoro-2-methoxy-3-pyridylmethanol; 3-Pyridinemethanol, 5-fluoro-2-methoxy-; 5-Fluoro-2-methoxy-pyridin-3-yl-methanol
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-Methoxy-Pyridin-3-Yl)-Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and adherence to ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.