Description

1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]-3-Piperidinecarboxylic Acid is a high-value, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining a substituted pyridine ring with a piperidine carboxylic acid moiety. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought after by research institutions, agrochemical developers, and pharmaceutical companies engaged in the discovery and production of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated pyridine structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final steps of API synthesis for specialized, small-molecule therapeutics.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalytic systems or diagnostic agents.

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]-3-Piperidinecarboxylic Acid
CAS No.	874800-69-8
Molecular Formula	C12H10ClF3N2O2
Molecular Weight	306.67 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid; 874800-69-8; 1-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]piperidine-3-carboxylic acid; 2-(3-Carboxypiperidin-1-yl)-3-chloro-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]-3-Piperidinecarboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a quality system designed to meet the expectations of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.