Description

Ethyl 7-Methyl-2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its imidazopyridine core and trifluoromethyl group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific bioactivity and metabolic stability. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing complex APIs, leveraging the imidazopyridine moiety for its potential biological activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities for various disease targets.
• Agrochemical Intermediate: Potential application in the synthesis of novel crop protection agents, where the trifluoromethyl group can enhance biological efficacy and environmental stability.
• Material Science Research: Investigated as a potential component in the development of organic electronic materials due to its conjugated heterocyclic structure.

Basic Information

Product Name	Ethyl 7-Methyl-2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylate
CAS No.	874776-54-2
Molecular Formula	C12H11F3N2O2
Molecular Weight	272.23 g/mol
Synonyms	Ethyl 7-methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate; Imidazo[1,2-a]pyridine-3-carboxylic acid, 7-methyl-2-(trifluoromethyl)-, ethyl ester; 874776-54-2; 7-Methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester; Ethyl 7-methyl-2-(trifluoromethyl)-imidazo[1,2-a]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 7-Methyl-2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.