Description

8-Methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique imidazopyridine scaffold combined with a carboxylic acid handle and a trifluoromethyl group, enabling precise molecular design for enhanced bioactivity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, anti-infectives, and anti-inflammatory agents.
• Agrochemical Research: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development in heterocyclic and fluorine chemistry.

Basic Information

Product Name	8-Methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic Acid
CAS No.	874776-53-1
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	8-Methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid; Imidazo[1,2-a]pyridine-3-carboxylic acid, 8-methyl-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-8-methylimidazo[1,2-a]pyridine-3-carboxylic acid; 874776-53-1; 8-Methyl-2-trifluoromethylimidazo[1,2-a]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support regulatory filings with comprehensive documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.