Description

2-{[5-(Trifluoromethyl)Pyridin-2-Yl]Amino}Ethanol is a high-value trifluoromethylpyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecules, particularly in the development of novel active ingredients where the trifluoromethyl group enhances metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific molecular scaffold.

Basic Information

Product Name	2-{[5-(Trifluoromethyl)Pyridin-2-Yl]Amino}Ethanol
CAS No.	874630-03-2
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	2-((5-(Trifluoromethyl)pyridin-2-yl)amino)ethanol; 2-[(5-Trifluoromethyl-2-pyridinyl)amino]ethanol; 2-[(5-Trifluoromethylpyridin-2-yl)amino]ethan-1-ol; 2-Aminoethanol, N-[5-(trifluoromethyl)-2-pyridinyl]-; Ethanol, 2-[[5-(trifluoromethyl)-2-pyridinyl]amino]-; 2-Hydroxyethyl[5-(trifluoromethyl)pyrid-2-yl]amine
EINECS	Contact for details

Quality Control

Our 2-{[5-(Trifluoromethyl)Pyridin-2-Yl]Amino}Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.