Description

3-Chloro-2-Ethoxy-5-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring chloro, ethoxy, and nitro substituents on a pyridine core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-2-Ethoxy-5-Nitropyridine
CAS No.	874492-07-6
Molecular Formula	C7H7ClN2O3
Molecular Weight	202.60 g/mol
Synonyms	3-Chloro-2-ethoxy-5-nitropyridine; 2-Ethoxy-3-chloro-5-nitropyridine; 5-Nitro-3-chloro-2-ethoxypyridine; Pyridine, 3-chloro-2-ethoxy-5-nitro-; 874492-07-6; 3-Chloro-2-ethoxy-5-nitro-pyridine; 2-Ethoxy-5-nitro-3-chloropyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Ethoxy-5-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.