Description

1-(6-Ethynyl-Pyridin-2-Yl)-Ethanone is a high-purity organic building block featuring a pyridine core functionalized with an ethynyl and an acetyl group. This compound is valued for its versatility as a key intermediate in advanced organic synthesis, particularly in the construction of complex heterocyclic systems and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its molecular scaffold can be incorporated into compounds with specific biological activity.
• Material Science & Catalysis: Acts as a precursor for creating specialized ligands in catalytic systems and for synthesizing advanced organic materials, including conductive polymers and metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds, facilitating studies in medicinal chemistry and synthetic methodology.
• Life Sciences Reagent: Utilized as a biochemical probe or a tagged molecule in bioconjugation chemistry for diagnostic and research applications.

Basic Information

Product Name	1-(6-Ethynyl-Pyridin-2-Yl)-Ethanone
CAS No.	874379-35-8
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	1-(6-Ethynylpyridin-2-yl)ethanone; 2-Acetyl-6-ethynylpyridine; 6-Ethynyl-2-acetylpyridine; Ethanone, 1-(6-ethynyl-2-pyridinyl)-; 2-Pyridineacetylene, 6-acetyl-; 1-(6-Ethynyl-2-pyridinyl)ethanone
EINECS	Contact for details

Quality Control

Our 1-(6-Ethynyl-Pyridin-2-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.