Description

2-Cyanopyridin-3-Ylboronic Acid is a versatile and highly functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecular architectures through efficient cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine and nitrile functionalities.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a pivotal boronic acid coupling partner for forming carbon-carbon bonds to construct biaryl and heterobiaryl systems.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Cyanopyridin-3-Ylboronic Acid
CAS No.	874290-88-7
Molecular Formula	C6H5BN2O2
Molecular Weight	147.93 g/mol
Synonyms	(2-Cyanopyridin-3-yl)boronic Acid; 3-Borono-2-cyanopyridine; 2-Cyano-3-pyridineboronic Acid; 2-Cyanopyridine-3-boronic Acid; 3-Pyridineboronic Acid, 2-cyano-; Boronic acid, B-(2-cyano-3-pyridinyl)-; 874290-88-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Cyanopyridin-3-Ylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.