Description

4-(5-Oxopyrazolidin-3-Yl)Phenylboronic Acid is a specialized boronic acid derivative featuring a pyrazolidinone moiety, making it a valuable bifunctional building block in synthetic chemistry. Its primary value lies in its dual reactivity, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the heterocyclic core offers a handle for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating complex molecular architectures. The CAS number for this compound is 874290-64-9.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting inflammation, central nervous system (CNS) disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in constructing advanced active ingredients for crop protection agents, such as herbicides and fungicides with specific modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of functional polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized for creating activity-based probes or bioconjugates due to its potential for selective binding and further chemical modification.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for method development and exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	4-(5-Oxopyrazolidin-3-Yl)Phenylboronic Acid
CAS No.	874290-64-9
Molecular Formula	C9H11BN2O3
Molecular Weight	206.01 g/mol
Synonyms	3-[4-(Boronophenyl)]-5-pyrazolidinone; [4-(5-Oxo-2-pyrazolin-3-yl)phenyl]boronic acid; 4-(5-Oxo-4,5-dihydro-1H-pyrazol-3-yl)benzeneboronic acid; 3-(4-Boronophenyl)-2-pyrazolin-5-one; B-[4-(5-Oxo-4,5-dihydro-1H-pyrazol-3-yl)phenyl]boronic acid; 4-(5-Oxopyrazolidin-3-yl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-(5-Oxopyrazolidin-3-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.