Description

tert-Butyl 3-(Pyridin-3-yl)pyrrolidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a versatile pyrrolidine scaffold. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and novel bioactive molecules.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a key building block in the production route for potential Active Pharmaceutical Ingredients (APIs), especially those targeting neurological and oncological pathways.
• Chemical Library Development: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against various biological targets.
• Process Chemistry: Used in route scouting and scale-up studies for the development of efficient and cost-effective manufacturing processes.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry studies and the exploration of new heterocyclic reactions.

Basic Information

Product Name	tert-Butyl 3-(Pyridin-3-yl)pyrrolidine-1-carboxylate
CAS No.	874218-24-3
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-Boc-3-(3-pyridyl)pyrrolidine; 3-Pyridin-3-ylpyrrolidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(3-pyridinyl)-1-pyrrolidinecarboxylate; 1-(tert-Butoxycarbonyl)-3-(pyridin-3-yl)pyrrolidine; 3-(3-Pyridyl)pyrrolidine-1-carboxylic acid tert-butyl ester; Boc-3-(3-pyridyl)pyrrolidine; N-Boc-3-(3-pyridyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Pyridin-3-yl)pyrrolidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.