Description

3-(5-Bromo-Pyridin-3-Yl)-Prop-2-Yn-1-Ol is a high-purity brominated pyridine derivative featuring a propargylic alcohol functional group, making it a versatile and valuable synthetic intermediate. This compound is essential for constructing complex molecular architectures in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency and reliability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in click chemistry and bioconjugation strategies to create probes for studying biological processes.
• Ligand Synthesis: Acts as a precursor for synthesizing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Employed in exploratory chemistry for discovering new reactions and synthesizing novel heterocyclic compounds.

Basic Information

Product Name	3-(5-Bromo-Pyridin-3-Yl)-Prop-2-Yn-1-Ol
CAS No.	873302-37-5
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	5-Bromo-3-(2-hydroxyethynyl)pyridine; 3-(5-Bromo-3-pyridinyl)-2-propyn-1-ol; 5-Bromo-3-ethynylpyridin-3-ol; 3-(5-Bromopyridin-3-yl)prop-2-yn-1-ol; 5-Bromo-3-(prop-2-yn-1-ol)pyridine; 3-(5-Bromo-3-pyridyl)propargyl alcohol; 5-Bromo-3-(2-propynyl)pyridin-3-ol
EINECS	Contact for details

Quality Control

Every batch of 3-(5-Bromo-Pyridin-3-Yl)-Prop-2-Yn-1-Ol is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards typical for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles by HPLC, NMR, and MS is provided with each shipment to guarantee reliable and reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.