Description

3-Iodo-5-Methoxy-Pyridine is a versatile halogenated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in the strategic positioning of iodine and methoxy groups, which facilitate selective cross-coupling reactions and functional group transformations. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, especially in developing kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its reactivity to create new active compounds.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic electronic materials, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form biaryl and other complex structures.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes, tags, and affinity labels for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Iodo-5-Methoxy-Pyridine
CAS No.	873302-36-4
Molecular Formula	C6H6INO
Molecular Weight	235.02 g/mol
Synonyms	5-Methoxy-3-iodopyridine; 3-Iodo-5-methoxypyridine; 5-Methoxy-3-pyridinyl iodide; Pyridine, 3-iodo-5-methoxy-; 3-Iodo-5-methoxy-pyridin; 873302-36-4; 3-Jod-5-methoxypyridin
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Methoxy-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.