Description

2-[1-(Boc-Amino)Cyclopropyl]Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a cyclopropyl ring and a Boc-protected amine group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential therapeutic activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Protease Inhibitor Research: Used in the development of protease inhibitors due to its structural motifs.
• Kinase Inhibitor Synthesis: Serves as a precursor in the creation of targeted kinase inhibitors for oncology and other therapeutic areas.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptidomimetics to improve metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized for creating specialized probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-[1-(Boc-Amino)Cyclopropyl]Pyridine
CAS No.	873221-80-8
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	2-[1-[(tert-Butoxycarbonyl)amino]cyclopropyl]pyridine; 1-(Pyridin-2-yl)cyclopropan-1-amine, N-Boc-protected; tert-Butyl [1-(pyridin-2-yl)cyclopropyl]carbamate; Boc-ACPP; 2-(1-(Boc-amino)cyclopropyl)pyridine; N-Boc-1-(2-pyridyl)cyclopropylamine; (1-(Pyridin-2-yl)cyclopropyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-[1-(Boc-Amino)Cyclopropyl]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.