Description

5-Iodo-2-(Trifluoromethyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both iodine and a trifluoromethyl group, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine core.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Iodo-2-(Trifluoromethyl)Pyridine
CAS No.	873107-98-3
Molecular Formula	C6H3F3IN
Molecular Weight	272.99 g/mol
Synonyms	2-(Trifluoromethyl)-5-iodopyridine; 5-Iodo-2-trifluoromethylpyridine; 5-Iodo-α,α,α-trifluoro-2-picoline; Pyridine, 5-iodo-2-(trifluoromethyl)-; 873107-98-3
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.