Description

tert-Butyl 2-Methyl-5-Nitrobenzoate is a high-purity organic intermediate characterized by its nitro-substituted benzoate ester structure. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in the development of complex pharmaceutical molecules and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a nitro-aromatic precursor.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where its aromatic nitro group serves as a critical functional handle.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty organic compounds requiring a protected carboxylic acid group and an aromatic nitro moiety.
• Academic & Industrial Research: Serves as a valuable reagent in organic chemistry research for method development and exploring novel chemical transformations.
• Material Science Precursor: Potential use in the synthesis of organic ligands, monomers, or other components for advanced polymeric materials.

Basic Information

Product Name	tert-Butyl 2-Methyl-5-Nitrobenzoate
CAS No.	873005-25-5
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	2-Methyl-5-nitrobenzoic acid tert-butyl ester; Benzoic acid, 2-methyl-5-nitro-, 1,1-dimethylethyl ester; tert-Butyl 2-methyl-5-nitrobenzoate; 5-Nitro-o-toluic acid tert-butyl ester; 1,1-Dimethylethyl 2-methyl-5-nitrobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methyl-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.