Description

6-(Hydroxymethyl)-4-Mercaptopyridin-3-Ol is a high-purity, multi-functional heterocyclic building block featuring both hydroxymethyl and mercapto groups on a pyridine core. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Chelating Agent Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation.
• Bioconjugation Chemistry: The reactive thiol (-SH) and hydroxyl (-OH) groups enable its use in linker chemistry for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme activity.

Basic Information

Product Name	6-(Hydroxymethyl)-4-Mercaptopyridin-3-Ol
CAS No.	872714-70-0
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	4-Mercapto-6-(hydroxymethyl)pyridin-3-ol; 3-Pyridinol, 6-(hydroxymethyl)-4-mercapto-; 4-Mercapto-6-(hydroxymethyl)-3-pyridinol; 6-(Hydroxymethyl)-4-mercapto-3-pyridinol; 4-Thiol-6-(hydroxymethyl)pyridin-3-ol; 872714-70-0; 6-Hydroxymethyl-4-mercaptopyridin-3-ol
EINECS	Contact for details

Quality Control

Our 6-(Hydroxymethyl)-4-Mercaptopyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. Due to its hygroscopic and easily oxidized nature, the container should be opened only under controlled, moisture-free conditions and the contents used promptly.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.