Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxamide, 5-Bromo-N-Methyl- is a high-purity brominated pyrrolopyridine derivative, a crucial advanced pharmaceutical intermediate. This compound matters for its role as a key building block in the synthesis of complex, biologically active molecules, particularly kinase inhibitors. Pharmaceutical R&D and fine chemical synthesis teams need it to develop new therapeutic agents targeting various diseases, ensuring precise molecular construction and reliable batch-to-batch consistency for downstream processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies during drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic frameworks in custom synthesis and contract manufacturing.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring chemical biology.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxamide, 5-Bromo-N-Methyl-
CAS No.	872620-93-4
Molecular Formula	C9H8BrN3O
Molecular Weight	254.09 g/mol
Synonyms	5-Bromo-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide; 5-Bromo-N-methyl-7-azaindole-3-carboxamide; 5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxamide, N-methyl-; 872620-93-4; 5-Bromo-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid amide; N-Methyl-5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxamide, 5-Bromo-N-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with stringent specifications for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.