Description

C-(4-Trifluoromethyl-Pyridin-2-Yl)-Methylamine is a high-value, multi-functional organic building block featuring a pyridine core substituted with a trifluoromethyl group and an aminomethyl side chain. This compound is critical for medicinal chemistry and agrochemical research, where its unique trifluoromethylated heterocyclic structure imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and crop protection industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Facilitates the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	C-(4-Trifluoromethyl-Pyridin-2-Yl)-Methylamine
CAS No.	872577-05-4
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	2-(Aminomethyl)-4-(trifluoromethyl)pyridine; (4-Trifluoromethyl-2-pyridinyl)methanamine; 1-(4-Trifluoromethylpyridin-2-yl)methanamine; 2-Pyridinemethanamine, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)pyridine-2-methylamine; α-Amino-4-(trifluoromethyl)-2-picoline; 2-(Aminomethyl)-α,α,α-trifluoro-p-xylene (pyridine analog)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of C-(4-Trifluoromethyl-Pyridin-2-Yl)-Methylamine is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. We maintain strict adherence to internal specifications and can provide research-grade or development-grade material as required. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.