Description

1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its fused pyrrolopyridine core structure makes it a valuable intermediate for constructing complex molecules with potential biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a precursor for organic ligands and functional molecules used in catalysis and advanced materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology development in university and CRO laboratories.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid
CAS No.	872355-64-1
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid; 5-Carboxy-1H-pyrrolo[3,2-b]pyridine; Pyrrolo[3,2-b]pyridine-5-carboxylic acid; 872355-64-1; 1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid; 5-Pyrrolo[3,2-b]pyridinecarboxylic acid; 1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid (ACI)
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP-compliant manufacturing for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.