Description

3-Iodo-6-Mercaptopyridine is a versatile heterocyclic building block featuring both an iodine substituent and a thiol group, enabling diverse functionalization pathways. This compound is critical for the synthesis of complex molecules in pharmaceutical and agrochemical research, where precise molecular architecture is required. It is primarily sought after by R&D chemists and process development scientists in the life sciences and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactivity for creating sulfur-containing bioactive compounds.
• Ligand Precursor: Serves as a precursor for metal-chelating ligands in catalysis and materials science.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Functional Material Research: Employed in the development of organic electronic materials and self-assembled monolayers (SAMs).
• Bioconjugation Chemistry: The thiol group allows for site-specific conjugation to proteins, peptides, and other biomolecules.

Basic Information

Product Name	3-Iodo-6-Mercaptopyridine
CAS No.	872273-28-4
Molecular Formula	C5H4IN1S1
Molecular Weight	237.06 g/mol
Synonyms	6-Mercapto-3-iodopyridine; 3-Iodopyridine-6-thiol; 3-Iodo-6-pyridinethiol; 6-Thiol-3-iodopyridine; 3-Iodo-6-thiopyridinol; Pyridine, 3-iodo-6-mercapto-; 872273-28-4; 3-Iodo-6-mercapto-pyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-Mercaptopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.