Description

(6-Chloropyridin-3-Yl)-Cyclopropyl-Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine and cyclopropyl ketone structure. This compound is of significant commercial importance as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and manufacturing organizations within the agrochemical and pharmaceutical sectors for developing new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a foundational scaffold for developing new generation pesticides and herbicides with novel modes of action.
• Ligand Synthesis: Used in medicinal chemistry for creating specialized ligands in catalyst systems and receptor-binding studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	(6-Chloropyridin-3-Yl)-Cyclopropyl-Methanone
CAS No.	872088-06-7
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	Cyclopropyl(6-chloropyridin-3-yl)methanone; 6-Chloro-3-cyclopropanoylpyridine; 3-Acetyl-6-chloropyridine, cyclopropyl analog; (6-Chloro-3-pyridinyl)cyclopropylmethanone; 1-(6-Chloropyridin-3-yl)cyclopropan-1-one; CPCM; 872088-06-7
EINECS	Contact for details

Quality Control

Our (6-Chloropyridin-3-Yl)-Cyclopropyl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.