Description

tert-Butyl 4-Cyano-2-Fluorobenzoate is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its molecular structure, featuring both a cyano and a fluorine substituent on an aromatic ring protected by a tert-butyl ester, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: The protected ester and electron-withdrawing groups allow for selective further functionalization in complex multi-step syntheses.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	tert-Butyl 4-Cyano-2-Fluorobenzoate
CAS No.	872018-02-5
Molecular Formula	C12H12FNO2
Molecular Weight	221.23 g/mol
Synonyms	4-Cyano-2-fluorobenzoic acid tert-butyl ester; 2-Fluoro-4-cyanobenzoic acid tert-butyl ester; tert-Butyl 2-fluoro-4-cyanobenzoate; Benzoic acid, 4-cyano-2-fluoro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-cyano-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyano-2-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.