Description

Pent-2-Enoic Acid (2S,3S)-3-Dibenzylamino-2-Hydroxy-4-Phenylbutyl Ester is a sophisticated chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure pharmaceuticals and bioactive molecules. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for constructing complex molecular architectures, particularly in protease inhibitor and peptide mimetic research.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Protease Inhibitor Synthesis: Serves as a core structural component in the synthesis of peptidomimetic compounds designed to inhibit specific enzymatic targets.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce defined chiral centers into complex organic molecules.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to improve drug candidate potency and selectivity.
• Fine Chemical Production: Used in the multi-step synthesis of high-value, specialty chemicals for research and small-scale commercial applications.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring novel synthetic methodologies and bioorganic chemistry.

Basic Information

Product Name	Pent-2-Enoic Acid (2S,3S)-3-Dibenzylamino-2-Hydroxy-4-Phenylbutyl Ester
CAS No.	871949-03-0
Molecular Formula	C30H33NO3
Molecular Weight	455.59 g/mol
Synonyms	(2S,3S)-3-(Dibenzylamino)-2-hydroxy-4-phenylbutyl pent-2-enoate; (2S,3S)-3-(Bis(phenylmethyl)amino)-2-hydroxy-4-phenylbutyl 2-pentenoate; 2-Pentenoic acid, 3-(dibenzylamino)-2-hydroxy-4-phenylbutyl ester, (2S,3S)-; 871949-03-0; (2S,3S)-3-(Dibenzylamino)-2-hydroxy-4-phenylbutyl (E)-pent-2-enoate; DBAPB-Pentenoate; Chiral Amino Alcohol Pentenoate Ester
EINECS	Contact for details

Quality Control

Our Pent-2-Enoic Acid (2S,3S)-3-Dibenzylamino-2-Hydroxy-4-Phenylbutyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2S,3S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.