Description

Rac 2-Chloro Nicotine CAS NO 871894-35-8 is a halogenated derivative of nicotine, serving as a key chiral intermediate and reference standard in advanced chemical synthesis. This compound matters for its utility in the development and analytical validation of novel pharmaceutical agents and agrochemicals. It is primarily needed by research institutions and industrial manufacturers focused on nicotinic receptor studies, medicinal chemistry, and the production of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates targeting neurological pathways.
• Agrochemical Research: Used in the development and study of next-generation insecticides and plant growth regulators.
• Chemical Reference Standard: Serves as an analytical standard in HPLC, GC-MS, and NMR for quality control and method development.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore modifications of the nicotine scaffold.
• Biochemical Research: Utilized in vitro studies to investigate the binding and functional properties of nicotinic acetylcholine receptors (nAChRs).
• Fine Chemical Synthesis: Acts as a specialized precursor for the preparation of more complex, functionalized organic molecules.

Basic Information

Product Name	Rac 2-Chloro Nicotine
CAS No.	871894-35-8
Molecular Formula	C₁₀H₁₃ClN₂
Molecular Weight	196.68 g/mol
Synonyms	(±)-2-Chloronicotine; rac-2-Chloronicotine; 2-Chloro-3-(1-methyl-2-pyrrolidinyl)pyridine; DL-2-Chloronicotine; 1-Methyl-2-(6-chloro-3-pyridyl)pyrrolidine; Nicotine, 2-chloro-; 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine, 2-chloro- (racemic)
EINECS	Contact for details

Quality Control

Our Rac 2-Chloro Nicotine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.