Description

Pyridine-3-Carboximidamide Hemihydrate Hydrochloride is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a precursor in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its utility in constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Chemical Research: Serves as a versatile precursor in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and coordination chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Pyridine-3-Carboximidamide Hemihydrate Hydrochloride
CAS No.	871825-82-0
Molecular Formula	C6H8N3·HCl·½H2O
Molecular Weight	177.61 g/mol (anhydrous basis)
Synonyms	3-Amidinopyridine Hemihydrate Hydrochloride; Nicotinamidine Hemihydrate Hydrochloride; Pyridine-3-carboximidamide monohydrochloride hemihydrate; 3-Pyridinecarboximidamide, monohydrochloride, hemihydrate; 3-Cyanopyridine amidine hydrochloride hemihydrate; 3-Amidinopyridine HCl hemihydrate; 3-Pyridylamidine hydrochloride hemihydrate
EINECS	Contact for details

Quality Control

Our Pyridine-3-Carboximidamide Hemihydrate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	3.0% - 5.0% (Theoretical for hemihydrate: ~5.1%)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.