Description

tert-Butyl 4,5-Dihydro-1H-Pyrazolo[3,4-C]Pyridine-6(7H)-Carboxylate is a high-purity, protected heterocyclic building block essential for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate in the construction of complex molecules, particularly for kinase inhibitors and other biologically active agents. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used for scaffold elaboration and structure-activity relationship (SAR) studies in early-stage drug discovery.
• Process Chemistry: Serves as a starting material or advanced intermediate in the development of scalable, GMP-compliant synthetic routes for active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: The protected amine and heterocyclic core can be functionalized to create chemical probes for biological target identification and validation.
• Library Synthesis: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 4,5-Dihydro-1H-Pyrazolo[3,4-C]Pyridine-6(7H)-Carboxylate
CAS No.	871726-73-7
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	6-Boc-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridine; tert-Butyl 4,5,6,7-tetrahydropyrazolo[3,4-c]pyridine-6-carboxylate; 4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-c]pyridine-6-carboxylic acid tert-butyl ester; 6-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridine; 1H-Pyrazolo[3,4-c]pyridine-6(7H)-carboxylic acid, 4,5-dihydro-, 1,1-dimethylethyl ester; Boc-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridine; 6-Boc-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4,5-Dihydro-1H-Pyrazolo[3,4-C]Pyridine-6(7H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.