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Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione, 1-(3-Aminophenyl)-3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl- CAS NO 871701-87-0
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CAS No.:871701-87-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione, 1-(3-Aminophenyl)-3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl- is a sophisticated heterocyclic organic compound designed for advanced research and development. This molecule serves as a critical pharmacological intermediate or reference standard in the discovery of new therapeutic agents. It is primarily sought by pharmaceutical R&D teams and contract research organizations (CROs) working on targeted drug discovery programs.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and targeted therapy research.
- Kinase Inhibitor Research: Potential scaffold for the development of selective kinase inhibitors due to its pyrido[4,3-d]pyrimidine trione core structure.
- Chemical Biology Probe: Used as a tool compound to study specific biological pathways and protein-ligand interactions in academic and industrial labs.
- Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical chemistry laboratories.
- Medicinal Chemistry Optimization: Provides a versatile core for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
- Preclinical Development: Supplied for use in early-stage in vitro and in vivo testing of new chemical entities.
Basic Information
| Product Name | Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione, 1-(3-Aminophenyl)-3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl- |
| CAS No. | 871701-87-0 |
| Molecular Formula | C24H21FIN5O3 |
| Molecular Weight | 597.26 g/mol |
| Synonyms | 1-(3-Aminophenyl)-3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-1H,3H,6H,8H-pyrido[4,3-d]pyrimidine-2,4,7-trione; 1-(3-Aminophenyl)-3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione; UNII-9F8S9W7G0C; 9F8S9W7G0C; 871701-87-0; 1-(3-Aminophenyl)-3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-1H,3H,6H,8H-pyrido[4,3-d]pyrimidine-2,4,7-trione; 5-[(2-Fluoro-4-iodophenyl)amino]-1-(3-aminophenyl)-3-cyclopropyl-6,8-dimethyl-1H,3H,6H,8H-pyrido[4,3-d]pyrimidine-2,4,7-trione |
| EINECS | Contact for details |
Quality Control
Our Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione derivative is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, supporting traceability and compliance for research and development applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and opened in a dry environment to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥95.0% (Area %) |
| Water Content (KF) | ≤1.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Heavy Metals | <20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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