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Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione, 1-(3-Aminophenyl)-3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl- CAS NO 871701-87-0


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CAS No.:871701-87-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione, 1-(3-Aminophenyl)-3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl- is a sophisticated heterocyclic organic compound designed for advanced research and development. This molecule serves as a critical pharmacological intermediate or reference standard in the discovery of new therapeutic agents. It is primarily sought by pharmaceutical R&D teams and contract research organizations (CROs) working on targeted drug discovery programs.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and targeted therapy research.
  • Kinase Inhibitor Research: Potential scaffold for the development of selective kinase inhibitors due to its pyrido[4,3-d]pyrimidine trione core structure.
  • Chemical Biology Probe: Used as a tool compound to study specific biological pathways and protein-ligand interactions in academic and industrial labs.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical chemistry laboratories.
  • Medicinal Chemistry Optimization: Provides a versatile core for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
  • Preclinical Development: Supplied for use in early-stage in vitro and in vivo testing of new chemical entities.

Basic Information

Product Name Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione, 1-(3-Aminophenyl)-3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl-
CAS No. 871701-87-0
Molecular Formula C24H21FIN5O3
Molecular Weight 597.26 g/mol
Synonyms 1-(3-Aminophenyl)-3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-1H,3H,6H,8H-pyrido[4,3-d]pyrimidine-2,4,7-trione; 1-(3-Aminophenyl)-3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione; UNII-9F8S9W7G0C; 9F8S9W7G0C; 871701-87-0; 1-(3-Aminophenyl)-3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-1H,3H,6H,8H-pyrido[4,3-d]pyrimidine-2,4,7-trione; 5-[(2-Fluoro-4-iodophenyl)amino]-1-(3-aminophenyl)-3-cyclopropyl-6,8-dimethyl-1H,3H,6H,8H-pyrido[4,3-d]pyrimidine-2,4,7-trione
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Quality Control

Our Pyrido[4,3-D]Pyrimidine-2,4,7(1H,3H,6H)-Trione derivative is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, supporting traceability and compliance for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and opened in a dry environment to prevent degradation.

Specification

Item Specification
Appearance Off-white to light yellow solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥95.0% (Area %)
Water Content (KF) ≤1.0%
Residual Solvents (GC) Complies with ICH guidelines
Heavy Metals <20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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