Description

2-(5-Bromopyridin-2-Yl)-2-Methylpropanenitrile is a high-value brominated pyridine derivative and a versatile nitrile-containing building block. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic and nitrile functionalities.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	2-(5-Bromopyridin-2-Yl)-2-Methylpropanenitrile
CAS No.	871239-58-6
Molecular Formula	C9H9BrN2
Molecular Weight	225.09 g/mol
Synonyms	2-(5-Bromo-2-pyridinyl)-2-methylpropanenitrile; 2-Methyl-2-(5-bromopyridin-2-yl)propanenitrile; 5-Bromo-2-(2-cyano-2-propyl)pyridine; 2-(5-Bromopyridin-2-yl)-2-methylpropionitrile; α,α-Dimethyl-5-bromo-2-pyridineacetonitrile; 871239-58-6; 5-Bromo-2-(1-cyano-1-methylethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(5-Bromopyridin-2-Yl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.