Description

4-Pyridin-3-Yl-1,3-Dihydro-Imidazole-2-Thione Hydrochloride is a high-purity heterocyclic organic compound, specifically a functionalized imidazole-2-thione derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for developing novel pharmaceuticals and agrochemicals, particularly in creating molecules with specific biological activity. This product is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, inflammation, or as kinase inhibitors.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, such as fungicides or herbicides.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Ligand Synthesis: Acts as a starting material for synthesizing complex ligands used in catalysis and material science.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for novel heterocyclic chemistry research.
• Custom Synthesis: A fundamental building block for custom synthesis and scale-up projects requiring specific imidazole-thione chemistry.

Basic Information

Product Name	4-Pyridin-3-Yl-1,3-Dihydro-Imidazole-2-Thione Hydrochloride
CAS No.	871237-64-8
Molecular Formula	C8H8N3S·HCl
Molecular Weight	215.69 g/mol (Free base: 179.23 g/mol)
Synonyms	3-(2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)pyridine hydrochloride; 4-(3-Pyridinyl)-2-imidazolinethione hydrochloride; 1,3-Dihydro-4-(3-pyridinyl)-2H-imidazole-2-thione hydrochloride; 4-(Pyridin-3-yl)-4,5-dihydro-1H-imidazole-2-thiol hydrochloride; 4-(3-Pyridyl)-2-imidazolinethione hydrochloride; 4-(3-Pyridinyl)-1,3-dihydro-2H-imidazole-2-thione hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Pyridin-3-Yl-1,3-Dihydro-Imidazole-2-Thione Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.