Description

3-Pyridinepropanoic Acid, 6-(Trifluoromethyl)-, Methyl Ester is a high-value trifluoromethylated pyridine derivative, a key building block in advanced organic synthesis. Its structure combines a pyridine core with a trifluoromethyl group and an ester functionality, offering unique reactivity and physicochemical properties for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with tailored electronic or surface properties.
• Chemical Biology Probes: Useful for developing molecular probes and tags due to the distinctive spectroscopic signature of the trifluoromethyl group.

Basic Information

Product Name	3-Pyridinepropanoic Acid, 6-(Trifluoromethyl)-, Methyl Ester
CAS No.	871224-67-8
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Methyl 3-(6-(trifluoromethyl)pyridin-3-yl)propanoate; 3-(6-(Trifluoromethyl)-3-pyridinyl)propanoic Acid Methyl Ester; Methyl 6-(Trifluoromethyl)nicotinate Propionate; 6-Trifluoromethyl-3-pyridinepropionic Acid Methyl Ester; 3-(6-Trifluoromethylpyridin-3-yl)propionic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinepropanoic Acid, 6-(Trifluoromethyl)-, Methyl Ester adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.