Description

1-Pyrrolidinecarboxylic Acid, 3-[[(1R)-1-(1-Naphthalenyl)Ethyl]Amino]-, 1,1-Dimethylethyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of pharmaceuticals and biologically active molecules, particularly those targeting specific enantiomeric pathways. It is primarily needed by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of complex, optically pure compounds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a ligand or precursor in catalytic systems for enantioselective transformations.
• Medicinal Chemistry Research: Serves as a scaffold for constructing novel molecular libraries in drug discovery programs.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex target molecules.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 3-[[(1R)-1-(1-Naphthalenyl)Ethyl]Amino]-, 1,1-Dimethylethyl Ester
CAS No.	870859-04-4
Molecular Formula	C21H28N2O2
Molecular Weight	340.46 g/mol
Synonyms	(R)-tert-Butyl 3-((1-(naphthalen-1-yl)ethyl)amino)pyrrolidine-1-carboxylate; (R)-1-Boc-3-((1-(1-naphthyl)ethyl)amino)pyrrolidine; tert-Butyl (3R)-3-[[(1R)-1-(1-naphthyl)ethyl]amino]-1-pyrrolidinecarboxylate; 1-Pyrrolidinecarboxylic acid, 3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-, 1,1-dimethylethyl ester, (3R)-; (R)-1-Boc-3-((1-(naphthalen-1-yl)ethyl)amino)pyrrolidine; 870859-04-4; (R)-tert-Butyl 3-((1-(naphthalen-1-yl)ethyl)amino)pyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed to confirm identity, purity, and enantiomeric excess, with specifications tailored to meet the stringent requirements of pharmaceutical R&D and production. Certificates of Analysis (COA) detailing chromatographic purity (HPLC), chiral purity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.