Description

(E)-1-[(1S)-1-(4-Fluorophenyl)Ethyl]-3-[3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Benzylidene]Piperidin-2-One is a high-purity, non-racemic chiral compound featuring a complex molecular architecture designed for advanced pharmaceutical research. This compound serves as a critical advanced pharmaceutical intermediate or reference standard in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D organizations and contract research and manufacturing (CRO/CMO) companies engaged in drug discovery programs targeting complex diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold or a sophisticated precursor for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical manufacturing.
• Biochemical Probe Development: Potential utility in creating tool compounds for investigating specific biological pathways and target validation.
• Asymmetric Synthesis: Employed in chiral synthesis due to its defined stereocenter, aiding in the production of enantiomerically pure drug candidates.
• Process Chemistry: Used in scaling up and optimizing synthetic routes for potential clinical and commercial drug production.

Basic Information

Product Name	(E)-1-[(1S)-1-(4-Fluorophenyl)Ethyl]-3-[3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Benzylidene]Piperidin-2-One
CAS No.	870843-42-8
Molecular Formula	C25H26FN3O2
Molecular Weight	419.50 g/mol
Synonyms	(E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-{[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene}piperidin-2-one; 870843-42-8; (E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methylimidazol-1-yl)benzylidene]piperidin-2-one; (2E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-{[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene}piperidin-2-one; UNII-9F3G6J8Q2T; 9F3G6J8Q2T; CHEMBL3185147; BDBM50389353.
EINECS	Contact for details

Quality Control

Our (E)-1-[(1S)-1-(4-Fluorophenyl)Ethyl]-3-[3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Benzylidene]Piperidin-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.