Description

n-[(1R)-3-(Dimethylamino)-1-(Hydroxymethyl)-3-Oxopropyl]Carbamic Acid Phenylmethyl Ester is a high-purity, chiral organic intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its complex molecular architecture, which serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research institutions and manufacturers engaged in the production of sophisticated therapeutic agents, particularly within the fields of oncology, neurology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and investigational new drugs.
• API Development: Serves as a crucial precursor in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations required for biological activity.
• Peptidomimetic Research: Acts as a building block in the design and synthesis of peptide analogs and mimetics for drug discovery.
• Chemical Biology Probes: Used in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Process Chemistry Optimization: Employed in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.

Basic Information

Item	Details
Product Name	n-[(1R)-3-(Dimethylamino)-1-(Hydroxymethyl)-3-Oxopropyl]Carbamic Acid Phenylmethyl Ester
CAS No.	870812-29-6
Molecular Formula	C15H22N2O4
Molecular Weight	294.35 g/mol
Synonyms	(R)-Benzyl (3-(dimethylamino)-1-hydroxy-3-oxopropyl)carbamate; (R)-Benzyl 3-(dimethylamino)-1-hydroxy-3-oxopropylcarbamate; (1R)-3-(Dimethylamino)-1-(hydroxymethyl)-3-oxopropyl carbamic acid benzyl ester; (R)-Benzyl N-[3-(dimethylamino)-1-hydroxy-3-oxopropyl]carbamate; Benzyl (R)-3-(dimethylamino)-1-hydroxy-3-oxopropylcarbamate; (R)-Cbz-β-hydroxy-β'-dimethylaminoalanine benzyl ester analog
EINECS	Contact for details

Quality Control

Our n-[(1R)-3-(Dimethylamino)-1-(Hydroxymethyl)-3-Oxopropyl]Carbamic Acid Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.