Description

6-(Di-Boc-Amino)-2-Bromopyridine is a high-purity, protected amine building block essential for advanced organic synthesis. This compound is specifically designed to facilitate the controlled introduction of amino functionality into complex molecular architectures, offering chemists a versatile and stable intermediate. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for introducing protected amine groups into heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where specific pyridine-based structures are required.
• Ligand Preparation: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of advanced polymers and functional materials with tailored properties.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in academic and industrial research laboratories.

Basic Information

Product Name	6-(Di-Boc-Amino)-2-Bromopyridine
CAS No.	870703-61-0
Molecular Formula	C₁₆H₂₃BrN₂O₄
Molecular Weight	387.27 g/mol
Synonyms	2-Bromo-6-[(tert-butoxycarbonyl)amino]pyridine; 2-Bromo-6-[(Boc)₂N]pyridine; 6-Amino-2-bromopyridine, N,N-di-Boc protected; Di-tert-butyl (6-bromopyridin-2-yl)imidodicarbonate; 2-Bromo-6-(bis(tert-butoxycarbonyl)amino)pyridine; 6-(Di-tert-butoxycarbonylamino)-2-bromopyridine; N,N-Di-Boc-6-amino-2-bromopyridine
EINECS	Contact for details

Quality Control

Our 6-(Di-Boc-Amino)-2-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.