Description

(S)-Ethyl 2-(4-Hydroxy-2-Oxopyrrolidin-1-Yl)Acetate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the construction of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of enantiomerically pure synthons for producing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• API Synthesis: Used in the production route of complex Active Pharmaceutical Ingredients (APIs) requiring a defined stereochemical center.
• Agrochemical Research: Serves as a precursor in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where stereochemical purity is paramount.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in academic and contract research organizations (CROs).
• Peptidomimetic Synthesis: Used in the design and synthesis of peptidomimetics and proline-derived compounds.

Basic Information

Product Name	(S)-Ethyl 2-(4-Hydroxy-2-Oxopyrrolidin-1-Yl)Acetate
CAS No.	870695-39-9
Molecular Formula	C8H13NO4
Molecular Weight	187.19 g/mol
Synonyms	Ethyl (S)-2-(4-Hydroxy-2-oxopyrrolidin-1-yl)acetate; 1-(Ethoxycarbonylmethyl)-4-hydroxy-2-pyrrolidinone; (S)-1-(Carbethoxymethyl)-4-hydroxy-2-pyrrolidinone; (S)-1-(Ethoxycarbonylmethyl)-4-hydroxy-2-pyrrolidinone; (S)-4-Hydroxy-1-(2-ethoxy-2-oxoethyl)pyrrolidin-2-one; (S)-N-(Ethoxycarbonylmethyl)-4-hydroxy-2-pyrrolidinone; 870695-39-9; (S)-Enantiomer of Ethyl 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetate
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 2-(4-Hydroxy-2-Oxopyrrolidin-1-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.