Description

(3R,4S,5S)-tert-Butyl 4-(Benzyl(Methyl)Amino)-3-Methoxy-5-Methylheptanoate is a high-purity, stereochemically defined chiral building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with precise three-dimensional architecture, which is critical for developing pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and method development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for complex therapeutic agents.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce specific chiral centers into target molecules.
• Process Chemistry: Serves as a key starting material or intermediate in the scale-up and optimization of synthetic routes for drug candidates.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the synthesis of compound libraries for biological screening.
• Agrochemical Synthesis: Potential intermediate in the production of chiral pesticides or herbicides where specific stereochemistry impacts biological activity.
• Catalyst and Ligand Development: Can be utilized in the synthesis of novel chiral catalysts or ligands for enantioselective transformations.

Basic Information

Product Name	(3R,4S,5S)-tert-Butyl 4-(Benzyl(Methyl)Amino)-3-Methoxy-5-Methylheptanoate
CAS No.	870640-64-5
Molecular Formula	C21H35NO3
Molecular Weight	349.51 g/mol
Synonyms	tert-Butyl (3R,4S,5S)-4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate; 4-(Benzyl(methyl)amino)-3-methoxy-5-methyl-heptanoic acid tert-butyl ester; (3R,4S,5S)-4-(N-Benzyl-N-methylamino)-3-methoxy-5-methylheptanoic acid tert-butyl ester; Heptanoic acid, 4-(benzyl(methyl)amino)-3-methoxy-5-methyl-, 1,1-dimethylethyl ester, (3R,4S,5S)-; BMTE Ester; Chiral Heptanoate Ester Intermediate
EINECS	Contact for details

Quality Control

Our (3R,4S,5S)-tert-Butyl 4-(Benzyl(Methyl)Amino)-3-Methoxy-5-Methylheptanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, supporting compliance with cGMP and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.