Description

1-[(4-Chlorophenyl)Sulphonyl]-4-(Hydroxymethyl)Piperidine, 4-Chlorophenyl 4-(Hydroxymethyl)Piperidin-1-Yl Sulphone is a high-purity, functionalized piperidine derivative featuring both a sulphonyl linker and a hydroxymethyl group, making it a versatile building block for advanced chemical synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where precise molecular architecture is critical. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the sulphonyl and piperidine moieties can contribute to biological activity.
• Organic Synthesis Reagent: Serves as a versatile synthon in medicinal and combinatorial chemistry for constructing complex heterocyclic frameworks.
• Material Science Precursor: Potential use in the synthesis of functional polymers or ligands for catalysts due to its reactive hydroxymethyl group.
• Chemical Biology Probe Development: Employed in creating tool compounds for studying biological pathways and protein interactions.

Basic Information

Product Name	1-[(4-Chlorophenyl)Sulphonyl]-4-(Hydroxymethyl)Piperidine, 4-Chlorophenyl 4-(Hydroxymethyl)Piperidin-1-Yl Sulphone
CAS No.	870529-81-0
Molecular Formula	C12H16ClNO3S
Molecular Weight	289.78 g/mol
Synonyms	4-Chlorophenyl 4-(hydroxymethyl)piperidin-1-yl sulfone; 1-[(4-Chlorophenyl)sulfonyl]-4-(hydroxymethyl)piperidine; 4-(Hydroxymethyl)-1-[(4-chlorophenyl)sulfonyl]piperidine; 1-(4-Chlorobenzenesulfonyl)-4-(hydroxymethyl)piperidine; 4-(Hydroxymethyl)-N-(4-chlorophenyl)piperidine-1-sulfonamide; 870529-81-0; 4-Chlorophenyl 4-(hydroxymethyl)-1-piperidinesulfonate
EINECS	Contact for details

Quality Control

Our 1-[(4-Chlorophenyl)Sulphonyl]-4-(Hydroxymethyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring consistent quality and traceability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.