Description

Methyl 4-Bromo-3-Methylthieno-[2,3-C]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 870244-28-3. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its precise molecular architecture that enables the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the controlled construction of complex heterocyclic cores found in potential therapeutic molecules.
• Chemical Biology Probes: Employed in the development of specialized molecular probes for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis methodologies and new chemical entity development.

Basic Information

Product Name	Methyl 4-Bromo-3-Methylthieno-[2,3-C]Pyridine-2-Carboxylate
CAS No.	870244-28-3
Molecular Formula	C11H8BrNO2S
Molecular Weight	302.16 g/mol
Synonyms	Methyl 4-bromo-3-methylthieno[2,3-c]pyridine-2-carboxylate; 4-Bromo-3-methylthieno[2,3-c]pyridine-2-carboxylic acid methyl ester; Thieno[2,3-c]pyridine-2-carboxylic acid, 4-bromo-3-methyl-, methyl ester; 870244-28-3; Methyl 4-bromo-3-methylthieno(2,3-c)pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Bromo-3-Methylthieno-[2,3-C]Pyridine-2-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled and stored under appropriate conditions to maintain stability. Keep away from strong bases and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.