Description

3-Fluoro-4-(Hydroxymethyl)Pyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is highly valued for its unique molecular architecture, which combines a reactive hydroxymethyl group with a fluorine substituent on the pyridine ring, enabling precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biomolecules for metabolic pathway studies and imaging applications.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Fluoro-4-(Hydroxymethyl)Pyridine
CAS No.	870063-60-8
Molecular Formula	C6H6FNO
Molecular Weight	127.11 g/mol
Synonyms	4-(Hydroxymethyl)-3-fluoropyridine; 3-Fluoro-4-pyridinemethanol; (3-Fluoropyridin-4-yl)methanol; 3-Fluoro-4-(hydroxymethyl)pyridine; 3-Fluoro-4-pyridylcarbinol; 870063-60-8; 3-Fluoro-4-hydroxymethylpyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Hydroxymethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.