Description

C-(2-Chloro-5-Fluoro-Pyridin-3-Yl)-Methylamine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyridine core. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a molecular probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.
• Material Science: Potential use in the synthesis of functionalized polymers and advanced organic electronic materials.

Basic Information

Product Name	C-(2-Chloro-5-Fluoro-Pyridin-3-Yl)-Methylamine
CAS No.	870063-53-9
Molecular Formula	C7H6ClFN2
Molecular Weight	172.59 g/mol
Synonyms	(2-Chloro-5-fluoropyridin-3-yl)methanamine; 3-(Aminomethyl)-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-3-pyridinemethanamine; 2-Chloro-5-fluoro-3-(aminomethyl)pyridine; 870063-53-9; C-(2-Chloro-5-Fluoro-3-Pyridyl)Methylamine; 3-(Aminomethyl)-2-chloro-5-fluoropyridine
EINECS	Contact for details

Quality Control

Our C-(2-Chloro-5-Fluoro-Pyridin-3-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.