Description

2-Chloro-5-Fluoro-3-(Hydroxymethyl)Pyridine is a high-value pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure with a hydroxymethyl functional group makes it an essential intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions in fine chemical production.
• Material Science Research: Intermediate for creating functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Chloro-5-Fluoro-3-(Hydroxymethyl)Pyridine
CAS No.	870063-52-8
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	3-(Hydroxymethyl)-2-chloro-5-fluoropyridine; (2-Chloro-5-fluoropyridin-3-yl)methanol; 2-Chloro-5-fluoro-3-pyridinemethanol; 2-Chloro-5-fluoro-3-pyridylmethanol; 870063-52-8; 2-Chloro-5-fluoro-3-hydroxymethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoro-3-(Hydroxymethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.