Description

4-(5-Chloro-2-(Isopropylamino)Pyridin-4-Yl)-1H-Pyrrole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research organizations, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Serves as a core scaffold in the manufacturing process of final active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of tools for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	4-(5-Chloro-2-(Isopropylamino)Pyridin-4-Yl)-1H-Pyrrole-2-Carboxylic Acid
CAS No.	869886-90-8
Molecular Formula	C13H14ClN3O2
Molecular Weight	279.72 g/mol
Synonyms	1H-Pyrrole-2-carboxylic acid, 4-[5-chloro-2-[(1-methylethyl)amino]-4-pyridinyl]-; 4-(5-Chloro-2-(isopropylamino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid; 869886-90-8; 4-(5-Chloro-2-(propan-2-ylamino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid; 4-(5-Chloro-2-((1-methylethyl)amino)-4-pyridinyl)-1H-pyrrole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-(5-Chloro-2-(Isopropylamino)Pyridin-4-Yl)-1H-Pyrrole-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.