Description

2,3,4-Tri-o-Acetyl-β-L-Arabinopyranosyl 2,2,2-Trichloroacetimidate is a high-purity, advanced glycosyl donor intermediate essential for stereoselective glycosylation reactions. Its primary value lies in enabling the efficient and controlled synthesis of complex oligosaccharides and glycoconjugates, which are critical for pharmaceutical and biochemical research. This compound is particularly vital for medicinal chemists and process development scientists in the pharmaceutical industry working on carbohydrate-based drugs, vaccine development, and diagnostic reagents.

Application

• Glycosylation Reagent: A key building block for the stereospecific synthesis of L-arabinose-containing oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the research and development of novel carbohydrate-based therapeutics, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: Critical for constructing complex glycoconjugates used in vaccine development and targeted drug delivery systems.
• Biochemical Probes: Serves as a precursor for labeled sugars and probes used in glycobiology studies and diagnostic assays.
• Process Chemistry: Employed in scale-up and process optimization for the manufacturing of active pharmaceutical ingredients (APIs) with carbohydrate motifs.
• Academic Research: A valuable tool in synthetic organic chemistry laboratories for methodology development and total synthesis of natural products.

Basic Information

Product Name	2,3,4-Tri-o-Acetyl-β-L-Arabinopyranosyl 2,2,2-Trichloroacetimidate
CAS No.	869848-87-3
Molecular Formula	C13H16Cl3NO8
Molecular Weight	420.62 g/mol
Synonyms	2,3,4-Tri-O-acetyl-β-L-arabinopyranosyl 2,2,2-trichloroacetimidate; β-L-Arabinopyranosyl trichloroacetimidate, 2,3,4-triacetate; 1-O-(2,2,2-Trichloroethanimidoyl)-2,3,4-tri-O-acetyl-β-L-arabinopyranose; L-Arabinose trichloroacetimidate derivative; Glycosyl trichloroacetimidate donor (L-arabino); 869848-87-3; (2R,3S,4S)-5-[(2,2,2-Trichloroethanimidoyl)oxy]-3,4-bis(acetyloxy)oxan-2-yl acetate
EINECS	Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-β-L-Arabinopyranosyl 2,2,2-Trichloroacetimidate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical intermediates, ensuring traceability and regulatory compliance for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.