Description

2-Chloro-4-hydroxy-3-pyridinecarbonitrile is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring chloro, hydroxy, and nitrile functional groups on a pyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry and material science for creating libraries of novel compounds.
• Ligand and Catalyst Development: The functional groups can be utilized to develop novel ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	2-Chloro-4-hydroxy-3-pyridinecarbonitrile
CAS No.	869802-74-4
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	2-Chloro-4-hydroxynicotinonitrile; 3-Cyano-2-chloro-4-hydroxypyridine; 4-Hydroxy-2-chloro-3-cyanopyridine; 2-Chloro-4-oxo-1,4-dihydropyridine-3-carbonitrile; 2-Chloro-4-pyridinol-3-carbonitrile; 869802-74-4; 2-Chloro-4-hydroxypyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-4-hydroxy-3-pyridinecarbonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled to minimize prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.